The Impact of Magic Mushrooms on Personality and Behavior

Magic mushrooms, also known as psilocybin mushrooms, contain a psychoactive compound called psilocybin. When consumed, psilocybin interacts with serotonin receptors in the brain, leading to altered perception, cognition, and mood. The effects of magic mushrooms can vary widely, and there is growing interest in understanding their impact on personality and behavior. This discussion explores the potential effects of magic mushrooms on personality traits, emotional states, spirituality, and overall well-being. It is important to approach these substances with caution and proper guidance, as individual experiences can vary significantly.

Humans have used psychoactive mushrooms for thousands of years.

Psychoactive mushrooms have indeed been used by humans for thousands of years, primarily for their hallucinogenic properties and spiritual or ceremonial purposes. 

It’s important to note that the cultural and historical use of psychoactive mushrooms does not imply universal acceptance or endorsement. The legal status and social perception of these substances can vary significantly across different societies and jurisdictions.

A single high dose of hallucinogenic mushrooms can permanently alter a person’s personality for more than a year, according to a new study.

People who were given psilocybin, the compound found in “magic mushrooms” that causes hallucinations and feelings of transcendence, had a more “open” personality after their experience, which lasted at least 14 months. Openness is a psychological term that refers to a desire for new experiences. People who are more open have broad imaginations and place a high value on emotion, art, and curiosity.

According to study researcher Katherine MacLean, this personality warp is unusual because personality rarely changes much after the age of 25 or 30. (In fact, one recent study discovered that our personalities are pretty much set by first grade.) “This is one of the first studies to show that you can actually change adult personality,” explained MacLean, a postdoctoral researcher at The Johns Hopkins University School of Medicine.

According to MacLean, the root of the change appears to be the mystical experiences that psilocybin frequently induces. These profound, transcendent feelings, she claims, are no less real because they are chemically induced. [What Are Hallucinogens and How Do They Work?]

“Many years later, people are saying it was one of the most profound experiences of their lives,” MacLean said. “In that context, it’s not surprising that it might be permanent.”

Let’s explore the potential impact of magic mushrooms on personality and behavior.

  1. Openness to Experience: Research suggests that magic mushrooms can increase openness to experience, which is a personality trait associated with curiosity, imagination, and appreciation of art and aesthetics. Psilocybin may promote novel and creative thinking, leading to enhanced imaginative and introspective experiences.
  2. Emotional Effects: Magic mushrooms can induce a range of emotions, including euphoria, bliss, introspection, and even anxiety or fear during the psychedelic experience. The emotional impact largely depends on the individual’s mindset and the environment. Some individuals report long-term positive changes in mood and emotional well-being after a psilocybin experience.
  3. Spiritual and Mystical Experiences: Psilocybin has been associated with spiritual and mystical experiences, characterized by a sense of interconnectedness, awe, and transcendence. These experiences can lead to profound shifts in one’s worldview, increased personal meaning, and a sense of connection to something greater than oneself.
  4. Personality Changes: Some studies suggest that a single experience with psilocybin can lead to enduring changes in personality traits. The most consistent finding is an increase in openness to experience. Other potential changes include increased creativity, decreased neuroticism (emotional instability), and increased agreeableness, though further research is needed to establish these effects more conclusively.
  5. Behavior and Well-being: Magic mushrooms can influence behavior and well-being beyond personality traits. Some users report improved mood, increased empathy and social connection, and reduced symptoms of anxiety and depression following a psilocybin experience. These effects may be attributed to the altered perspective and increased insight gained during the psychedelic experience.


It’s worth noting that individual experiences and outcomes can vary significantly. While many people have positive and transformative experiences with magic mushrooms, some individuals may also experience negative or challenging episodes, especially when using high doses or in unfavorable settings. It’s important to approach these substances with caution, respect, and proper guidance, preferably under the supervision of trained professionals in a therapeutic or research context.

Furthermore, the legality of magic mushrooms varies across jurisdictions. It is essential to familiarize oneself with the laws and regulations of the specific region before considering their use.

Psilocybin Allows Them to Transcend their Worldviews

Yes, many individuals report profound and transformative experiences with psilocybin that can lead to a shift in their ways of thinking about the world. Psilocybin, the active compound in magic mushrooms, has been known to induce altered states of consciousness that can be characterized by a sense of unity, interconnectedness, and expanded awareness. These experiences may allow individuals to transcend their ordinary thought patterns and gain new perspectives on themselves, others, and the world around them.

Psilocybin can produce a range of effects, including enhanced introspection, increased creativity, and a dissolution of the ego boundaries, which can lead to a more holistic and interconnected view of reality. People often describe a sense of unity with nature, a feeling of interconnectedness with others and the universe, and a heightened sense of awe and wonder.

These transformative experiences can challenge deeply ingrained beliefs, attitudes, and ways of thinking, allowing individuals to question and reevaluate their assumptions about themselves and the world. This can lead to personal insights, increased self-awareness, and a greater appreciation for the complexities and interconnectedness of existence.

It’s important to note that the nature and depth of these experiences can vary greatly among individuals. Factors such as set (mindset) and setting (environment), dosage, and individual differences play a significant role in shaping the outcome of a psilocybin experience. Additionally, integrating and making sense of these experiences after the psychedelic journey is also crucial for long-term benefit.

Psilocybin-assisted therapy, conducted in controlled and supportive settings, has been explored as a potential treatment for mental health conditions such as depression, anxiety, and PTSD. The therapeutic process involves combining the effects of psilocybin with skilled therapy to facilitate the integration of the transformative experiences into daily life.

It’s worth noting that while psilocybin can have positive effects for many individuals, it is essential to approach its use responsibly, with proper preparation, guidance, and consideration for one’s mental and physical well-being. The recreational use of psilocybin mushrooms in uncontrolled environments carries potential risks and should be approached with caution.

The National Institute on Drug Abuse Conducted Research

The National Institute on Drug Abuse (NIDA) has supported research on various aspects of psilocybin, including its effects, potential therapeutic applications, and risks. While I don’t have access to the most recent studies funded by NIDA, I can provide some general information about their research involvement.

1) Therapeutic Applications: NIDA has supported research investigating the potential therapeutic uses of psilocybin. Studies have explored its efficacy in treating conditions such as depression, anxiety, addiction, and end-of-life distress in patients with life-threatening illnesses. These studies typically involve controlled settings, trained professionals, and rigorous methodologies to assess both the safety and effectiveness of psilocybin-assisted therapy.

2) Substance Abuse and Addiction: NIDA has also funded research on the potential of psilocybin in treating substance abuse and addiction. Studies have examined its effects on various substances, such as tobacco and alcohol dependence. The aim is to understand how psilocybin might influence addiction-related behaviors, cravings, and treatment outcomes.

3) Neuropharmacology and Mechanisms of Action: Research funded by NIDA has investigated the neuropharmacological effects of psilocybin, aiming to understand how it interacts with the brain’s serotonin system and other neural circuits. These studies contribute to our understanding of the mechanisms underlying subjective experiences, psychological effects, and potential therapeutic benefits of psilocybin.

4) Safety and Adverse Effects: NIDA-funded research has also focused on evaluating the safety profile and potential adverse effects of psilocybin. This includes examining its acute effects on physiological functions, psychological well-being, and long-term implications for mental health. Understanding the risks associated with psilocybin is crucial for its safe use and potential medical applications.

It’s important to note that while NIDA supports research on psilocybin, it does so within the context of investigating potential therapeutic benefits and understanding its effects on the brain and behavior. NIDA’s involvement does not necessarily imply endorsement or support for recreational or non-medical use of psilocybin mushrooms.

To access the most up-to-date and detailed information on NIDA-funded research regarding psilocybin, I recommend visiting the official website of the National Institute on Drug Abuse or exploring scientific literature and publications related to the topic.


In conclusion, the impact of magic mushrooms on personality and behavior is a complex and multifaceted topic. Research suggests that magic mushrooms, particularly psilocybin, can lead to temporary and long-term changes in various aspects of personality and behavior. Users may experience increased openness to experience, emotional effects ranging from euphoria to introspection, and potentially profound spiritual or mystical experiences. Personality changes, such as increased creativity and decreased neuroticism, have also been observed. Moreover, magic mushrooms have shown promise in therapeutic settings, helping individuals with conditions like depression, anxiety, and addiction. However, it is essential to approach the use of magic mushrooms responsibly, considering factors such as dosage, set and setting, and individual well-being. Further research is needed to fully understand the complexities of these effects and their long-term implications.